On January 10, 2019, the "Frequently Asked Questions on Cosmetics Supervision and Management (1)" issued by the State Drug Administration (hereinafter referred to as the State Food and Drug Administration) clearly stated that it is added to the cosmetic formula or the product claims to contain human oligopeptides. 1 or EGF, are illegal products.
This……
Isn't this a top-down blow to the newly-developed medical skincare professional line and the ever-expanding daily chemical line? After all, the medical professional line and the daily chemical line of biological skin care are gradually recognized by the effect of EGF, and there is a fissile development. To know, according to the market research report of the China Business Research Institute:
In 2018, the total market for medical beauty services in China may exceed RMB 125 billion.
It is expected that the market size will further increase to 300 billion yuan by 2022.
In the 2018 double 11 beauty products sales list, Chinese local brands HFP and Winona ranked 8th and 9th respectively, killing a number of international big names, and both of them are the main EGF repair freeze-dried powder products. In addition to HFP, Winona, Ripstose and other well-known brands. More than 2,000 cosmetic companies in China have launched EGF freeze-dried powder products. Now that EGF is banned, where is the way out for bio-skin repair products?
Is there a product that can replace EGF very well?
The answer is yes:
Fibronectin Fn has emerged in the cosmetics market!
What is fibronectin Fn?
A: Speaking of OsrFn, the Chinese name is rice recombinant human fibronectin, which is short for Recombinant Human Fibronectin, hereinafter referred to as fibronectin Fn, which is a high molecular weight (~450KDa) glycoprotein in the extracellular matrix. Subunits with a molecular mass of approximately 220 kDa are formed by interchain disulfide bonds and are widely distributed in body tissues.
Heyuan Biotechnology uses a world-leading high-tech-high-efficiency expression platform technology of rice endosperm cells (Oryz HiExp ) to culture human fibronectin with little or no activity in human cells, using rice planted by bioengineering technology. Production, and then extracted and purified from rice.
The high-efficiency expression platform technology of rice endosperm cells (Oryz HiExp ) has won the second prize of international technology invention in 2013 (the highest national award in the biological field), and has successfully planted a variety of human active proteins, such as rice recombinant human serum albumin OsrHSA. The injection has received clinical trial approvals for the country's Class I new drugs, and a number of Class I new drugs are being declared.
If you still question whether rice can grow human protein, you can find a professional with a student project in the surrounding area (the key points must be professional, this small series does not accept non-professional questions). Under the understanding of the students, you can also directly find the small series. Xiaobian can give you a detailed science for free, and increase your knowledge~
Does fibronectin function?
A: Although fibronectin Fn is a niche protein in the field of biological science and its application is relatively small, there are many domestic and foreign studies showing that fibronectin Fn does promote cell metabolism, anti-oxidation and anti-oxidation in beauty skin care. Decay, anti-allergic and other effects, the main mechanism of action is the growth-promoting effect on cells. Heyuan Bio-study beauty freeze-dried powder and mask also have the addition of fibronectin Fn, and the experience has also been unanimously recognized by the majority of Miss Amy. At the same time, Heyuan Bio R&D personnel used professional biological detection methods to detect and compare the effects of fibronectin Fn and natural fibronectin on cell growth.
Concentration and growth of CHO-K1 cells promoted by different concentrations of fibronectin Fn(OsrFn) and commercially available natural fibronectin
Comparison of different concentrations of fibronectin Fn (OsrFn) on epithelial cell adhesion and growth promotion Why choose OsrFn of Huyuan organism?
A: Commercially available fibronectin for life science research and biopharmaceutical research and development, most of which comes from human blood extraction. Due to limited source, it is difficult to scale, and there is a risk of infection of various potential blood parvoviruses such as AIDS and hepatitis B. The price is very expensive, 1mg is priced at a few hundred yuan, and this is the same as the biotechnology method of the Hu Yuan bio-reformed Fn, 200ug sold for thousands of dollars, so difficult to obtain and the price is thousands of times more expensive than gold "Noble protein" is really difficult to meet the development needs of the beauty industry.
Heyuan Bio uses the world's leading bioengineering technology. The OsrFn developed and produced comes from green safe and no blood virus risk. The purification process uses a high-grade pharmaceutical-grade process, colorless and odorless, and is made into lyophilized powder for easy storage. Transport and store to avoid loss of activity, only need to add sterile water to dissolve. Moreover, the rice varieties currently developed for the production of OsrFn can be planted on a large scale, and there is no need to worry about the shortage of supply.
The most important thing is that the price is also very beautiful~~
There are more biological skin care ingredients OsrHSA, LYZ, LF, bFGF, KGF, which can meet different skin care functional requirements and product variety development. Welcome to find a small detailed consultation product details phone, technical support online QQ
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