Propolis is a sticky secretion collected by a bee from a bud, bark, or stem wound of a plant. It mixes with its excrement and some beeswax to form a soft, sticky, solid, jelly-like substance. It is brown, grayish brown or bluish green, bitter and aromatic. Propolis is an effective substance used by bees to maintain the health of the entire population. A group of 5 to 60,000 bees can only produce 100-150 grams of propolis a year, which is known as “purple goldâ€. From the middle and late last century, scholars from all over the world have conducted in-depth research on propolis. It has been confirmed by scientists from various countries that propolis contains rich and unique bioactive substances. Propolis has various functions such as antibacterial, anti-inflammatory, anti-oxidation, immunity enhancement, blood sugar lowering, lipid-lowering, anti-cancer, and leukemia treatment. The role of health care has now become a hot topic for scientists in various countries, and has become an emerging health care product.
In 1967, Lindenfelser's research in the United States showed that propolis has inhibitory effects on 25 kinds of bacteria.
In 1975, China's housing columns and other tests have proved that propolis has a strong antibacterial effect on at least 10 species of bacteria.
In 1980, China's He Tianjun and others passed tests to prove that propolis has inhibitory effects on 14 species of bacteria, including pneumococci, E. coli, and P. aeruginosa.
In 1987, Zhang Zhen and others in China had anti-gastric ulcer effects.
In 1992, experiments conducted by Japan's Shimokazu Tetsuka also demonstrated that propolis has anti-inflammatory effects.
In 1994, Japan’s Matsuno Tetsuka also demonstrated that propolis has an inhibitory effect on 16 species of bacteria, including pneumococcus, Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhimurium.
In 1995, Zalesky demonstrated that propolis has the effect of promoting tissue cell regeneration.
In 1996, China’s Cheng Wenxian and others passed tests to prove that propolis has a significant inhibitory effect on periodontal disease pathogens (after which propolis toothpaste was developed).
In the last century, China used propolis as a key research project for the Ninth Five-Year Plan. Through the unremitting efforts of many scientific and technical workers, propolis contains more than 300 natural ingredients. These ingredients are beneficial to human health. To date, propolis has been identified as containing at least 20 amino acids and more than 50 kinds of Aromatic compounds, six terpenoids, more than thirty kinds of flavonoids, dozens of terpenes, thirty trace elements, and other substances such as enzymes, phenols, esters, polysaccharides, vitamins, etc. Among the many effective components of propolis, caffeic acid phenethyl ester (CAPE) has been identified as one of the main components of propolis, and has a wide range of pharmacological activities. Many of the effects of propolis are related to CAPE. related.
Other studies have shown that propolis ethanol extract containing CAPE can inhibit carrageenan-induced adjuvant arthritis, pleurisy, and rat paw edema. Extracts that do not contain CAPE have no such activity, indicating CAPE is exerted. The main component of anti-inflammatory effects. In addition, CAPE can inhibit the production of NO. N0 is a free radical produced by iNOS to catalyze the production of L-arginine. Excessive NO can cause damage to the body, and in autoimmune diseases such as rheumatoid arthritis and ulcerative colon. Inflammation and NO synthesis in systemic lupus erythematosus increase.
In 1967, Lindenfelser's research in the United States showed that propolis has inhibitory effects on 25 kinds of bacteria.
In 1975, China's housing columns and other tests have proved that propolis has a strong antibacterial effect on at least 10 species of bacteria.
In 1980, China's He Tianjun and others passed tests to prove that propolis has inhibitory effects on 14 species of bacteria, including pneumococci, E. coli, and P. aeruginosa.
In 1987, Zhang Zhen and others in China had anti-gastric ulcer effects.
In 1992, experiments conducted by Japan's Shimokazu Tetsuka also demonstrated that propolis has anti-inflammatory effects.
In 1994, Japan’s Matsuno Tetsuka also demonstrated that propolis has an inhibitory effect on 16 species of bacteria, including pneumococcus, Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhimurium.
In 1995, Zalesky demonstrated that propolis has the effect of promoting tissue cell regeneration.
In 1996, China’s Cheng Wenxian and others passed tests to prove that propolis has a significant inhibitory effect on periodontal disease pathogens (after which propolis toothpaste was developed).
In the last century, China used propolis as a key research project for the Ninth Five-Year Plan. Through the unremitting efforts of many scientific and technical workers, propolis contains more than 300 natural ingredients. These ingredients are beneficial to human health. To date, propolis has been identified as containing at least 20 amino acids and more than 50 kinds of Aromatic compounds, six terpenoids, more than thirty kinds of flavonoids, dozens of terpenes, thirty trace elements, and other substances such as enzymes, phenols, esters, polysaccharides, vitamins, etc. Among the many effective components of propolis, caffeic acid phenethyl ester (CAPE) has been identified as one of the main components of propolis, and has a wide range of pharmacological activities. Many of the effects of propolis are related to CAPE. related.
Other studies have shown that propolis ethanol extract containing CAPE can inhibit carrageenan-induced adjuvant arthritis, pleurisy, and rat paw edema. Extracts that do not contain CAPE have no such activity, indicating CAPE is exerted. The main component of anti-inflammatory effects. In addition, CAPE can inhibit the production of NO. N0 is a free radical produced by iNOS to catalyze the production of L-arginine. Excessive NO can cause damage to the body, and in autoimmune diseases such as rheumatoid arthritis and ulcerative colon. Inflammation and NO synthesis in systemic lupus erythematosus increase.
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