Anti-inflammatory Drug Clobetasol propionate CAS: 25122-46-7 White Powder
Description:
Clobetasol propionate is classed as a very potent topical corticosteroid. Topical corticosteroids are also referred to as topical steroids. Topical steroids are used in addition to moisturisers (emollients) for treating inflammatory skin conditions such as eczema and dermatitis. A topical steroid is used when patches of eczema or dermatitis flare up. Clobetasol propionate relieves the symptoms of a flare-up by reducing inflammation, itching and redness. It is not a cure for the condition, but it will help to relieve the symptoms.
Basic information:
Chemical name: Clobetasol propionate
MF: C25H32ClFO5
MW: 466.97
CAS: 25122-46-7
Appearance: white powder
Purity: 99%
Usage: anti-inflammatory agent
COA:
Product name | Clobetasol propionate | ||
CAS No. | 25122-46-7 | Outer Packing | 1KG/bag |
Production date | Sep.,08, 2016 | Shelf life | Sep.,07, 2019 |
Standard adopted | USP38 | ||
Items of analysis | Specification | Results | |
Description | White or almost white crystalline powder | Almost white crystalline  powder | |
Solubility | Practically insoluble in water,slightly soluble in benzene and diethyl ether ,sparingly soluble ethanol  | Complies | |
Identification (IR) | Complies with the Standard | Complies | |
Specific Rotation | +98°~+104°  | +100.4° | |
Melting point | about 196ºC | 195.0ºC~197.0ºC | |
Loss on drying  | max.2.0% | 0.20% | |
Residue on ignition | max. 0.1% | 0.04% | |
Heavy Metals | max.20ppm | Complies | |
Single impurity | N.m.t 1.0% | 0.16% | |
Sum impurity | N.m.t 2.5% | 0.46% | |
Organic volatile impurities | meet the ICH requirement | Complies | |
Assay(HPLC,basisondrying) | 98.5%~102.0% | 99.9% | |
THF | Not more than 720ppm | Complies | |
Methanol | Not more than 3000ppm | Complies | |
DMF | Not more than 880ppm | Complies | |
Pyridine | Not more than 200ppm | Complies | |
Dichloromethane | Not more than 600ppm | Complies | |
Ethanol | Not more than 5000ppm | Complies | |
Acetone | Not more than 5000ppm | Complies | |
Conclusion | Qualified |
Uses:
Clobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis,psoriasis, and lichen sclerosus. It is also used to treat several auto-immune diseases including alopecia areata, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). It is used as first-line treatment for both acute and chronic GVHD of the skin.
Clobetasol proprionate is used cosmetically by dark-skinned women for skin whitening, although this use is controversial. The U.S. Food and Drug Administration has not approved it for that purpose, and sales without a prescription are illegal in the U.S. Nonetheless, it is often sold in U.S. retail beauty supply stores and on the internet. It is also sold internationally, and does not require a prescription in some countries. Whitening creams with clobetasol proprionate, such as Hyprogel, can make skin thin and easily bruised, with visible capillaries, and acne. It can also lead to hypertension, elevated blood sugar, suppression of the body's natural steroids, and stretch marks, which may be permanent.
Clobetasol propionate is, along with mercury and hydroquinone, "amongst the most toxic and most used agents in lightening products." Many products sold illegally have higher concentrations of clobetasol propionate than is permitted for prescription drugs.
Shipping methods and other details:Product Packaging
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag),or as required.
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery
Usually within 3-7 working days after payment.
Shipping
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;Â
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Service
we will try our best to satisfied you.
1. Tailor-made for every customers.Â
2. Third-party test for the products you demand.Â
3. Test your counter-samples and produce them for you.Â
4. Best discount for old customers.Â
5. Reasonable &Â competitive price, fast lead time.
6. Sample is available for your evaluation &Â Formulation development.
7. Faster delivery:Sample order in stock and 3-7 days for bulk production.
8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder
9. All inquiries will be replied within 12 hours.
10. Dedication to quality, supply &Â service.
11. Strictly on selecting raw materials.
After-Sale Service
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
Â
The quality control process
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before sellingÂ
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
Order Process and Tips :
Make an order | Please make clear what product and what quantity you need |
Mini Order | 10g |
Quote | Prices and Specifications details(COA) would be offered for you to consider and confirm. |
Payment ways | T/T, Western Union, Money Gram and Bitcoin |
Delivery ways | All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.) |
Shipping address | Provide your Valid and Correct destination address info(if possible with post code, phone number). |
Packing | Select best ways according to quantity and safety degree(Super discreet, professional and experienced) |
Lead time | Within 12 hours upon receipt of payment |
Package pictures | Photos of parcel would be offered to tell apart the items |
Tracking number | Offered once it is released |
Shipping time | About 5Â working days (Door-to-Door) |
After-sale service | 24/7 Online for any problems |
Please contact us if any more question or demand. Contact information:
Â
Anti-inflammatory Drug Clobetasol propionate CAS: 25122-46-7 White Powder
Description:
Clobetasol propionate is classed as a very potent topical corticosteroid. Topical corticosteroids are also referred to as topical steroids. Topical steroids are used in addition to moisturisers (emollients) for treating inflammatory skin conditions such as eczema and dermatitis. A topical steroid is used when patches of eczema or dermatitis flare up. Clobetasol propionate relieves the symptoms of a flare-up by reducing inflammation, itching and redness. It is not a cure for the condition, but it will help to relieve the symptoms.
Basic information:
Chemical name: Clobetasol propionate
MF: C25H32ClFO5
MW: 466.97
CAS: 25122-46-7
Appearance: white powder
Purity: 99%
Usage: anti-inflammatory agent
COA:
Product name | Clobetasol propionate | ||
CAS No. | 25122-46-7 | Outer Packing | 1KG/bag |
Production date | Sep.,08, 2016 | Shelf life | Sep.,07, 2019 |
Standard adopted | USP38 | ||
Items of analysis | Specification | Results | |
Description | White or almost white crystalline powder | Almost white crystalline  powder | |
Solubility | Practically insoluble in water,slightly soluble in benzene and diethyl ether ,sparingly soluble ethanol  | Complies | |
Identification (IR) | Complies with the Standard | Complies | |
Specific Rotation | +98°~+104°  | +100.4° | |
Melting point | about 196ºC | 195.0ºC~197.0ºC | |
Loss on drying  | max.2.0% | 0.20% | |
Residue on ignition | max. 0.1% | 0.04% | |
Heavy Metals | max.20ppm | Complies | |
Single impurity | N.m.t 1.0% | 0.16% | |
Sum impurity | N.m.t 2.5% | 0.46% | |
Organic volatile impurities | meet the ICH requirement | Complies | |
Assay(HPLC,basisondrying) | 98.5%~102.0% | 99.9% | |
THF | Not more than 720ppm | Complies | |
Methanol | Not more than 3000ppm | Complies | |
DMF | Not more than 880ppm | Complies | |
Pyridine | Not more than 200ppm | Complies | |
Dichloromethane | Not more than 600ppm | Complies | |
Ethanol | Not more than 5000ppm | Complies | |
Acetone | Not more than 5000ppm | Complies | |
Conclusion | Qualified |
Uses:
Clobetasol propionate is used for the treatment of various skin disorders including eczema, herpes labialis,psoriasis, and lichen sclerosus. It is also used to treat several auto-immune diseases including alopecia areata, lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). It is used as first-line treatment for both acute and chronic GVHD of the skin.
Clobetasol proprionate is used cosmetically by dark-skinned women for skin whitening, although this use is controversial. The U.S. Food and Drug Administration has not approved it for that purpose, and sales without a prescription are illegal in the U.S. Nonetheless, it is often sold in U.S. retail beauty supply stores and on the internet. It is also sold internationally, and does not require a prescription in some countries. Whitening creams with clobetasol proprionate, such as Hyprogel, can make skin thin and easily bruised, with visible capillaries, and acne. It can also lead to hypertension, elevated blood sugar, suppression of the body's natural steroids, and stretch marks, which may be permanent.
Clobetasol propionate is, along with mercury and hydroquinone, "amongst the most toxic and most used agents in lightening products." Many products sold illegally have higher concentrations of clobetasol propionate than is permitted for prescription drugs.
Shipping methods and other details:Product Packaging
1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag),or as required.
2) 25kg/drum (25kg net weight, 28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)
Storage
Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Delivery
Usually within 3-7 working days after payment.
Shipping
EMS,DHL, TNT, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service;Â
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;
Service
we will try our best to satisfied you.
1. Tailor-made for every customers.Â
2. Third-party test for the products you demand.Â
3. Test your counter-samples and produce them for you.Â
4. Best discount for old customers.Â
5. Reasonable &Â competitive price, fast lead time.
6. Sample is available for your evaluation &Â Formulation development.
7. Faster delivery:Sample order in stock and 3-7 days for bulk production.
8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder
9. All inquiries will be replied within 12 hours.
10. Dedication to quality, supply &Â service.
11. Strictly on selecting raw materials.
After-Sale Service
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
Â
The quality control process
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of products and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before sellingÂ
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
Order Process and Tips :
Make an order | Please make clear what product and what quantity you need |
Mini Order | 10g |
Quote | Prices and Specifications details(COA) would be offered for you to consider and confirm. |
Payment ways | T/T, Western Union, Money Gram and Bitcoin |
Delivery ways | All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.) |
Shipping address | Provide your Valid and Correct destination address info(if possible with post code, phone number). |
Packing | Select best ways according to quantity and safety degree(Super discreet, professional and experienced) |
Lead time | Within 12 hours upon receipt of payment |
Package pictures | Photos of parcel would be offered to tell apart the items |
Tracking number | Offered once it is released |
Shipping time | About 5Â working days (Door-to-Door) |
After-sale service | 24/7 Online for any problems |
Please contact us if any more question or demand. Contact information:
Â
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- Protein (e.g. protein powder)
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- Various vitamins (such as vitamin A, B vitamins, vitamin C, vitamin D, vitamin E, etc.)
- Minerals (e.g. calcium, iron, zinc, selenium, etc.)
- Dietary fiber
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