Oral Aicar Sarms White Solid Raw Material Aicar CAS: 2627-69-2 for Fat Burning

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Acadesine raw sarms powder
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Acadesine/AICAR Powder CAS:2627-69-2

Alias:AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE

CAS:2627-69-2

EINECS:220-097-5

Molecular Formula:C9H14N4O5

Molecular Weight:258.23

Apperance: White or off-white powder.

 

Acadesine/AICAR Powder Description:

AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide.It can also be known as AICA ribonucleotide, ZMP, or Acadesine.It is an intermediate contained in the generation of inosine monophosphate.It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production.

 

AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion.

 

With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion.Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.

 

Acadesine/AICAR Powder Biological Activity:

AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

 

Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro.

 

Acadesine/AICAR Powder Functions:

AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.

 

Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).

 

The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

 

COA:

 

 

4.Our Advabntage:

High quality with competitive price:

1) Standard: Enterprise Standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 

Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment. Tracking number available

2) Secure and discreet shipment. Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

Everybody is talking the similar words,what i want to say is:just give me a chance, just have a try on me, maybe you will get a surprise from me!


 

Acadesine raw sarms powder
SARMs powder Acadesine
Acadesine Bodybuilding
Acadesine Injection
Acadesine Cycle
Acadesine pure source
AICAR vendor


 

Acadesine/AICAR Powder CAS:2627-69-2

Alias:AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE

CAS:2627-69-2

EINECS:220-097-5

Molecular Formula:C9H14N4O5

Molecular Weight:258.23

Apperance: White or off-white powder.

 

Acadesine/AICAR Powder Description:

AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide.It can also be known as AICA ribonucleotide, ZMP, or Acadesine.It is an intermediate contained in the generation of inosine monophosphate.It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production.

 

AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion.

 

With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion.Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.

 

Acadesine/AICAR Powder Biological Activity:

AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

 

Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro.

 

Acadesine/AICAR Powder Functions:

AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.

 

Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).

 

The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

 

COA:

 

 

4.Our Advabntage:

High quality with competitive price:

1) Standard: Enterprise Standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 

Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment. Tracking number available

2) Secure and discreet shipment. Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

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