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When it comes to rejuvenation, what do you think of first?
I believe that everyone has seen that famous movie. Benjamin has grown up from the old shackles to the babies, showing us the emotional journey of family, love, friendship, dreams, loneliness, etc. in a lifetime, unique perspective and just right. Emotionality makes it one of the best films in history.
But let the rejuvenation happen in reality, what do you think? I think it's really cool.
In fact, our people have never given up on the chasing of young people and the resistance to aging. Even the monsters are tirelessly pursuing the immortality, let alone people. Especially the children of Taoism, they are almost a small expert in alchemy, and they are autocratic. Moreover, most of the descriptions of the old Taoist priests are "sacred winds and bones" as if they were young. In fact, Taoist people live long, mainly moving more and thinking less.
In fact, the first thing we must understand is that the rejuvenation in reality is not like turning a man into a baby from the old man in the movie. It is against the laws of nature, and God does not agree. Then, it is really necessary to realize the rejuvenation from the physiological point of view. What kind of realization is possible?
You look young: women starting from the skin
For the majority of female compatriots, compared with shoes, clothes and cosmetics, this creature of the boyfriend is dispensable. For boys, the girls’ dressing table is a bunch of large and small bottles and cans; but the girls can actually name each item in detail, its function, and the order of use...
This also fully shows that in order to stay young forever, skin care is always the first.
Even in the last century of material poverty, busy family women are not paying attention or having time to skin care, and will put a bottle of cream at home or a big treasure that they see every day.
The use of cosmetics at most is to delay the aging of the skin, the wrinkles will still wrinkle, the crow's feet can not play. So, how do you have a face that exudes a youthful and beautiful girllike look?
Baiyun said, be a child.
The skin surgery was first developed in Europe and the United States. In the 1980s, Japanese doctor Bai Bianfu made surgical measures for Asian face types. People's facial skin ages with age, and then wrinkles appear. Because of the influence of gravity, we often see that the whole face of the person is drooping when we are old, especially the silkworm part. And the skin surgery, as the name suggests, is to pull the skin up. Pulling the wrinkled skin tightly, the skin naturally looks smooth and flat, and it is not a dream to return to the age of twenty.
For this reason, skin surgery is also known as "rejuvenation." However, the skin surgery is also risky. After all, it is a knife on the face. If you accidentally damage the facial nerve, the trouble can be big. If it is not repaired for a long time, it is likely to cause permanent necrosis of the nerves. The return to youth is achieved, and facial paralysis can not be cured.
That Lapi is afraid of pulling his face, is there any way to avoid the knife? Proper injection of hyaluronic acid does have a very good wrinkle-reducing effect, making the skin more natural and shiny. But in reality, we also hear a lot of negative news, such as the possibility of causing facial expressions, etc., like a zombie face.
In other words, whether it is skin surgery or injection of hyaluronic acid, it relies on external force to achieve skin rejuvenation, but the role of external force will have a shelf life. After the expiration date, the user itself cannot accept sudden aging, such as from 25 to 45 years old, and will be reused again. This is another way of cutting and tying the needle, and the damage caused to the face should not be underestimated.
So, is there any other gentler and almost harmless way? Artificial skin can be very useful.
According to a study by the Massachusetts Institute of Technology, scientists have synthesized a transparent polymer film using polysiloxanes with good elasticity, gas permeability, adhesion and tensile strength. The user applies a gel containing this ingredient evenly to the skin, and then applies another gel containing a platinum gum component to form a film to protect the skin and reduce water loss. Moreover, it can be attached to the skin for more than 16 hours. With this layer of film, any wrinkled skin is immediately hidden.
Is this enough? No, MIT didn't stop. Two years later, it invented a water-based polymer gel. 95% of the ingredients are water, so it is highly compatible with the human body. It can also be used as a capsule coat, smart maker sticker, etc. due to its ability to implant a range of electronic devices. It is conceivable that if used to make artificial skin, combined with the research mentioned above, it would not be difficult to rejuvenate the skin.
But isn't the youthful chase that just stays on the surface of the skin the ultimate goal of mankind? This is obviously impossible. People want to understand what is causing the aging of the skin. Find this problem, then solve it, but also need to take a shot?
Exploring the human body, starting with the human body's password
There was a sensational news a few days ago. A startup, rejuvenate bio, announced that it could make it younger by introducing new DNA instructions into dogs after an initial test on a beagle dog. Moreover, their gene therapy has tested four morals of the Beavers Veterinary School in Boston last year.
This program is first used on dogs, and the economic benefits obtained are very objective. After all, everyone wants their pet dog to be with you for a long time. Since dogs are likely to rejuvenate, it is not impossible to use this technology for the benefit of mankind in the future.
In fact, using genetic intervention to help humanity is a hot topic.
Researchers at Stanford University believe that the process of aging is actually a process of cellular aging. If we can stop the aging of cells, then rejuvenation will be possible. So how to prevent cell aging? It is necessary to find genes that govern the aging of the human body. But if you find it, it still doesn't work. How to interfere with it? Studies have shown that an RNA called lncRNA (Longnon-coding RNA, long-chain non-coding RNA) plays a role in guiding, enhancing and even interfering with genes. Then, the researchers think that this work is like a set of programming, as long as the RNA can be blacked out, everything is in the hands of the human self.
There is an important technology called RNA modification. In the past two years, researchers have made important explorations and progress in this technology, and gradually revealed the molecular mechanism and function of modification. Techniques for detecting RNA modifications are being invented. If all goes well, then it is equivalent to shutting down the door to human aging. Is it not a good thing?
Relative to this mode of regulation, another way to use genetic technology to influence humans to return to youth is simple and rude.
The reason why the organs of the human body are aging is because of the aging of the organ cells, and the corresponding ability of stem cell division is also reduced. Then, after the activity of the neural stem cells in the brain is reduced, a mysterious group of resting neural stem cells will be used as a substitute. When the stem cells of this resting state are also spelled out, the human brain is almost the same. In March of this year, another group of researchers from Stanford University (yes, this school...) found that activating lysosomes in cells to degrade protein aggregates allowed the aging nerves in the brain to be at rest. Stem cells return to a "young state."
The significance of its technology is that the replacement of our neural stem cells can no longer be used. Then, rejuvenation and youthfulness are no longer a dream.
Compared with making a relatively easy-to-implement technology such as adding skin, using human power to control genes and cells is full of science and technology. However, deciphering the genetic code is destined to be a great and long-term project. We now push all the human representations to the genes, but the way we work is perhaps the tip of the iceberg. If you want to use your genes to change your traits, you may have more than enough time to live...
So, it sounds like an exciting way to come.
Someone changed the blood of the mouse, but some people want to use the blood of the young to return to the old child.
Blood is a magical thing. In the primitive society, some tribes saw blood as the source of life, and thus produced blood worship. In people's fantasy, fresh blood has become the favorite of female ghosts. In the American drama "True Love, Blood", the vampires are also eager for hundreds of thousands of years of age, and people are very happy.
In modern times, the rapid development of medicine satisfies the judgment of the blood "source of life". The rich biological indicators in the blood can accurately reflect the physiological abnormalities of human beings, so as to make early and more accurate diagnosis and treatment. Since blood is the source of life, then when people are old, will the blood of young people become younger?
This original guess seems to be becoming a little bit more realistic.
The change of blood makes the aging life become younger, but it is not a human but a mouse. As early as the mid-19th century, the French physiologist Paul Porter once stripped the skins of two white mice and stitched them together to create a circulatory system that shared blood. This experiment was successful. In the following hundred years, people have experimented with mice many times, and it has been proved that the blood of young mice does help to improve the memory, organ vitality and even life of old mice. Simply put, after the scientists' relay experiments, the exchange of blood has already allowed the mice to rejuvenate.
This makes scientists boldly guess: Is it possible to apply transfusion therapy to the human body?
So in 2016, Stanford University (yes, or me) joined the school's professor Weskerley to set up Alkahest to study whether young people's serum can help improve learning about Alzheimer's disease. The Silicon Valley venture capitalist Peter Deere is even more crazy. He directly registered a company, Ambrosia. People over the age of 35 can accept blood donation from young people under the age of 25 for only $8,000.
Experimenting with the human body is a matter of controversy. The first is that this is basically an unlikely event. Can blood flow together produce a chemical reaction? There is a complicated mechanism in this. If you change your youth, it is too simple to exchange old blood. The bigger controversy is that if the blood transfusion really makes the old people show the reverse growth of bodily functions to varying degrees, it will have a series of problems: whether the sudden increase in blood demand will trigger a new round of blood selling frenzy ? Will this lead to normal hospital blood stocks? Can the black blood sales industry chain be effectively regulated and investigated? Will it produce a new round of infectious diseases?
Perhaps when the exchange of blood makes people return to their twenties to become a reality, these doubts will be limited by the new system introduced. However, when a technology that may cause ethical and social problems is about to land, it is necessary to make countermeasures in advance so as not to be in a hurry.
In fact, rejuvenation, eternal life and even resurrection, on the one hand, shows people's nostalgia and reluctance to the beautiful real world, on the other hand, it also reflects the desire for life. But sometimes, think about it in reverse, is this a violation of the laws of the world? The old is not dead, the small is constantly being born, and in the long run is undoubtedly a burden on the society and the whole earth.
But when I think about it, perhaps every step of human exploration is not separated from the laws of nature. Human beings have wisdom, isn't it used to explore the unknown and the impossible, and then turn the imagination into reality? Perhaps the boundary of human thinking is the farthest we can reach. After all, I also want to live forever.
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