In the greenhouse, tomato seeds appeared, most of them were cracked from the flower pedicle, and the seeds exposed during cracking. The main reason was that flower organs and fruits could not develop normally.
Control measures 1. Select varieties that are not likely to produce deformed fruit, such as red jade, Hongbao, Xifen No. 3, Jiahong, Lichun and so on. 2. Reasonable use of plant growth regulators. Spray "multi-purpose" 200 times liquid or spray 25% of the booster at a concentration of 0.01% to properly control the weight. 3. When watering the tomato, rush irrigation without deep ploughing, press the proportion of 30 ml plus 15 kg of water, flush with the water; also can be combined with topdressing organic fertilizer, add 30 grams of organic fertilizer with 50 grams of Angra granules to enhance The permeability of the soil enhances the ability of tomato to absorb and absorb water. 4. It is found that the exposed fruit should be promptly removed. To prevent the occurrence of teratogenic fruit, it is recommended to spray the available boron and Indian calcium mixture at 600 to 800 times, spray once every 6 days, spray 2 or 3 times consecutively, and prevent tomato from occurring. Grain exposure has a good effect.
LCZ696 (Valsartan/sacubitril) is a combination drug for use in heart failure developed by Novartis. It consists of the angiotensin receptor blocker valsartan and the neprilysin inhibitor sacubitril, in a 1:1 mixture by molecule count. It may be used instead of an ACE inhibitor or an angiotensin receptor blocker in people with heart failure with reduced ejection fraction. The combination is sometimes described as an "angiotensin receptor-neprilysin inhibitor" (ARNi).
It was approved under the FDA's priority review process on July 7, 2015. It is also approved in Europe.
We produce a series of complete intermediates for LCZ696, intermediate I (CAS No. 1426129-50-1) and intermediate II (CAS No. 1012341-50-2) etc.
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