1. Animal species Suitable for monogastric animal probiotics The strains used are typically lactic acid bacteria, Bacillus, yeast, etc., and yeasts suitable for ruminants. 2. Animal physiological status Animals are in the stress period of external environmental changes and other conditions are the preconditions for the best effect of microecological agents. When the intestinal microflora of piglets is in good condition, the effect of microecological agents is small. 3, feed type and composition. 4, feed processing process. 5, strain composition and colonization ability. 6, the impact of water In general, the microbes in the dry state, the state of survival is better. When moisture rises, the survival rate decreases with time. Different bacteria have different tolerance to water. Spore-type bacteria are best tolerated, followed by cocci and streptococcus, and bacilli again. Different lactobacilli have different water stability. Lactobacillus plantarum is better and Lactobacillus acidophilus is poorer, and yeast is better tolerant to water. 7, temperature and pH. 8. Oxidation and bacteriostatic substances Most microbial strains are anaerobic or facultative anaerobic and have poor oxygen tolerance. Certain antibiotics, sulfa drugs, unsaturated fatty acids, mineral premixes, and concentrates are antibacterial substances that can reduce the activity of live bacteria. 9. Antibiotics and chemical synthetic antibacterial agents that are compatible with antibiotics and anticoccidial drugs have a killing effect on the microecological preparations and therefore cannot generally be used at the same time. 10. Preservation time As time goes on, the number of viable bacteria keeps decreasing. Bacillus is the most stable and the most stable is Bifidobacterium.
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