High-resolution LTQ-Orbitrap mass spectrometer for technical requirements for complete molecular weight determination

Determination of intact, tangentially and reduced mAb molecules by high resolution LTQ-Orbitrap mass spectrometry

For a monoclonal antibody with a molecular weight of 150,000 D, we can provide you with a molecular weight measurement with an error of less than 10 ppm compared to the theoretical value. In addition, we can also determine the molecular weight of the deglycosylated antibody after N-glycan removal, and the molecular weight of the light and heavy chain after reduction. Measurement accuracy is within +/- 10 ppm of theoretical molecular weight.
Technical process

Sample requirements

Avoid adding detergent to the sample, but you can have ions such as salt, urea, and guanidine hydrochloride. Monoclonal antibody content ≥ 10 μg; protein concentration ≥ 0.2 μg/μL

Technical advantages

1. The Principal mass spectrometer uses the Orbitrap mass analyzer. Oribtrap differs from other Time-of-flight (TOF) analyzers in that it measures the frequency of the magnetic field generated when ions rotate within an electrostatic field. The measurement frequency is our human stunt, so the measurement results are exceptionally accurate.
2. Professional data analysis software BiopharmaFinder3.0 SW-ReSpect algorithm.
3. Experienced operators and repeatedly optimized chromatographic, mass spectrometry and data algorithm parameters.
4. The test conditions are still being optimized, and the throughput and accuracy of the results will continue to increase.

case study

N Isopropylbenzylamine

ynephrine (or oxedrine) is a drug commonly used for weight loss. While its effectiveness is widely debated, synephrine has gained si

ynephrine (or oxedrine) is a drug commonly used for weight loss. While its effectiveness is widely debated, synephrine has gained significant popularity as an alternative to, a related substance which has been made illegal or restricted in many countries due to health risks and its use as a precursor in the illicit manufacturing.
There is however no occurrence of diverted synephrine for the manufacture of amphetamines, and the naturally occurring synephrine is, due to its phenolic group, unsuitable for such diversion.
Products containing bitter orange or synephrine are suspected of causing adverse cardiovascular reactions. Synephrine is derived primarily from the immature fruit of Citrus aurantium, a relatively small citrus tree, of which several of its more common names include Bitter Orange, Sour Orange, and Zhi shi. Dietary supplements generally supply single oral doses of 3–30 mg, while as a pharmaceutical agent it is given orally or by parenteral injection in 20–100 mg doses as a vasoconstrictor to hypotensive patients.

Our company offers variety of products which can meet your multifarious demands.including API Powder.Pharmaceutical Intermediates.Vitamins Powder.Plant Extracts.Food Additive.Peptide Powder and so on We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with anirresistible force.


Describe :

item
Synephrine hydrochloride
CAS No.
5985-28-4
Other Names
N-Isopropylnorsynephrine HCL
MF
C9H14ClNO2
EINECS No.
/
Place of Origin
China
Type
Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity
99%
Brand Name
Vanz
Model Number
Vanz20210420
Application
sport nutrition
Appearance
white powder
Product Name
Synephrine hydrochloride
CAS
5985-28-4
Appearance
white powder
Shelf life
2 Years
Package
25kg/drum
Certificate
ISO9001
Storage
Cool Dried Storage
Test Method
HPLC Test
Payment term
TT.Western Union .Credit Card
Assay
99%min
product name:

4b57171db3fc90722dc3ab4d45ba8b6

gnificant popularity as an alternative to, a related substance which has been made illegal or restricted in many countries due to health risks and its use as a precursor in the illicit manufacturing.
There is however no occurrence of diverted synephrine for the manufacture of amphetamines, and the naturally occurring synephrine is, due to its phenolic group, unsuitable for such diversion.
Products containing bitter orange or synephrine are suspected of causing adverse cardiovascular reactions. Synephrine is derived primarily from the immature fruit of Citrus aurantium, a relatively small citrus tree, of which several of its more common names include Bitter Orange, Sour Orange, and Zhi shi. Dietary supplements generally supply single oral doses of 3–30 mg, while as a pharmaceutical agent it is given orally or by parenteral injection in 20–100 mg doses as a vasoconstrictor to hypotensive patients.

Our company offers variety of products which can meet your multifarious demands.including API Powder.Pharmaceutical Intermediates.Vitamins Powder.Plant Extracts.Food Additive.Peptide Powder and so on We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with anirresistible force.


Describe :

item
Synephrine hydrochloride
CAS No.
5985-28-4
Other Names
N-Isopropylnorsynephrine HCL
MF
C9H14ClNO2
EINECS No.
/
Place of Origin
China
Type
Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity
99%
Brand Name
Vanz
Model Number
Vanz20210420
Application
sport nutrition
Appearance
white powder
Product Name
Synephrine hydrochloride
CAS
5985-28-4
Appearance
white powder
Shelf life
2 Years
Package
25kg/drum
Certificate
ISO9001
Storage
Cool Dried Storage
Test Method
HPLC Test
Payment term
TT.Western Union .Credit Card
Assay
99%min
product name:

4b57171db3fc90722dc3ab4d45ba8b6

N Isopropylbenzylamine,Inositol Powder,Best Inositol Powder,Benzylisopropylamine Cas 102-97-6

Shaanxi YXchuang Biotechnology Co., Ltd , https://www.peptidenootropics.com