What are the key foods that cause obesity? A recent study by scientists shows that the only factor that causes obesity in mice is the amount of fat in the diet. Related research has recently been published in the latest issue of the journal Cellular Metabolism.
The John Spikeman team of researchers at the Institute of Genetics and Development of the Chinese Academy of Sciences used mice to perform the largest experiments of its kind to date. They designed 30 different foods with different fat, carbohydrate (sugar) and protein content. The researchers used these foods to feed 5 different strains of mice for 3 months (equivalent to 9 years of human life). A total of more than 100,000 mouse body weight changes and body fat data were collected from the experiment, and the conclusions were very clear - the only factor that causes obesity in mice is the fat content of their diet.
The results also showed that foods with a sugar content of up to 30% did not cause an increase in body weight in mice, and the combined effects of sugar and fat did not increase fatr than fat alone. When mice eat fat, the delicious activates their brain reward mechanism pathway, leading to a further increase in their energy intake.
In the 1980s and 1990s, it was widely believed that dietary fat content was the most important factor in fattening. At the beginning of this century, there was a view that the content of refined carbohydrates such as carbohydrates, especially sugars, was the main cause of fat. More scholars have said that eating fat can save people from getting fat. Recently, the academic community turned to protein, and believes that when the protein content in the diet declines, in order to satisfy a certain amount of protein intake, people have to consume more food, resulting in more energy and fat.
The Spikeman team's experiments confirmed that the only factor that causes obesity in mice is the dietary fat content. Spiekman said that mice and humans have a lot in common in physiology and metabolism. "We can't do the same way for humans to do such long-term diet control research. Therefore, the evidence provided by the study is that we understand humans. The influence of the diet structure provides a good clue." (Reporter Li Daqing)
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