Vitamin D can effectively reduce the risk of colorectal cancer in the body

Recently, a research report published in the International Journal of the Journal of the National Cancer Institute, researchers from more than 20 institutions such as the Harvard School of Public Health found that the circulation in the body The high concentration of vitamin D or directly related to the risk of colorectal cancer, this study once again confirmed the protective effect of vitamin D found by researchers on the effective inhibition of colon cancer. In order to effectively prevent colorectal cancer, the optimal concentration of vitamin D used may be changed to the current recommendations of the National Academy of Medical Sciences (which is based solely on the promotion of bone health).

We all know that vitamin D plays a key role in the health of the body's bones, and researchers speculate that vitamin D can reduce the risk of colorectal cancer in a variety of ways through cell growth and regulation; previously reported inconsistent The study concluded that the higher concentration of circulating 25-hydroxyvitamin D (a recognized standard for measuring vitamin D status) is directly related to the reduced risk of colorectal cancer. So far, the researchers have performed vitamin D supplements. A small number of clinical trials between the risk of colorectal cancer have not found any effects, but the size of the study, the time of supplementation, and compliance may all lead to ineffective results for the researchers.

Researcher Dr. Stephanie Smith-Warner pointed out that in order to address the inconsistency of vitamin D in previous studies, and to investigate the association between vitamin D and the risk of colorectal cancer in the population subgroup, in this study we were from the United States. More than 5,700 colorectal cancer patients and 7,100 control individuals in Europe and Asia were studied; in the past, differences in assay methods made it difficult to integrate data on vitamin D from different studies, and the researchers in this paper Systematic analysis of the risks posed by vitamin D levels across a wide range of internationally using standard methods.

Individuals with insufficient vitamin D concentrations may increase their risk of developing colorectal cancer by 31% in an average 5-year study, compared to those considering circulating vitamin D concentrations associated with body bone health. Similarly, If the body's vitamin D concentration is higher than the concentration that maintains the body's bone health, the risk of cancer in the individual will be reduced by 22%. However, at the highest concentration, the risk of cancer in an individual does not seem to continue to decline. When compared to the concentration that maintains the health of the body's bones, these associated effects appear to be more pronounced in the female body than in men.

Women have a 4.2% risk of colorectal cancer in their lifetime, compared with 4.5% in men . Colorectal cancer is the third most common cancer in the world and the third leading cause of cancer death in the US population. The researchers predict 2018 There will be 140,250 new cases in the year, and there will be 50,630 deaths. Researcher Dr. Marji L. McCullough said that many health and wellness organizations do not recommend vitamin D as an effective means of preventing colorectal cancer, but in this study we have confirmed the association between vitamin D and the risk of colorectal cancer. Vitamin D can be obtained through diet , especially from fortified foods, supplements or sun exposure. Researchers recommend taking vitamin D as much as possible through diet, and sun exposure can be a potential cause of skin cancer.

Original source:

Marjorie L McCullough, Emilie S Zoltick, Stephanie J Weinstein, et al. Circulating Vitamin D and Colorectal Cancer Risk: An International Pooling Project of 17 Cohorts. JNCI: Journal of the National Cancer Institute (2018) doi:10.1093/jnci/djy087