Release date: 2017-10-26
Abionic, a Swiss biotech startup, developed an in vitro test device in 2012 to detect allergies in the testee within five minutes. The technology is now certified by the US Food and Drug Administration (FDA) for testing human allergies to cats, dogs, pollen and common plants and is expected to be available in the US market next year.
The device, called abioSCOPE, consists of a test device and a kit. The kit contains a blood sample collector, abioMIX reagent and a capsule. During the test, the blood of the test subject is collected by a collector, mixed with a fluorescently labeled abioMIX reagent, and the conjugate after the reaction is placed under a micro fluorescence microscope for detection. This microscope and the amplitude of the fluorescence can be detected to quantify the level of allergen antibody (IgE) in the subject. The test results can be transferred to its mobile application abioGUIDE in time.
Put the tray with the test sample into the test instrument and get the result in five minutes.
The diffusion of organisms in the solute is slow, which results in a general test that takes a long time to produce results. The key to abioSCOPE's rapid results is one of the devices called nanofluid biosensors.
The working principle of the device is to accelerate the interaction between biomolecules and blood in the solution by expanding the contact area and convection of the biomolecule and blood in the reagent, thereby quickly obtaining the test result, saving doctors and patients a lot of time.
Most of Abionic's researchers are from the Swiss Federal Institute of Technology in Lausanne. In addition to allergies, they are also experimenting with this technique to detect hemoglobin and sepsis in humans.
Abionic founder Nicolas Durand is a Ph.D. student at the Swiss Federal Institute of Technology. He applied nanotechnology to life sciences in his thesis, which later became the core of Abionic technology.
This type of technique, which does not enter the body and detects the body through saliva, urine, blood, etc., is called liquid biopsy.
At the beginning of this year, the Chinese University of Hong Kong researched and developed a technique for detecting potential cancerous changes in the human body using liquid biopsy. The formation of cancer is a long-term process. Before the cells just become cancerous but do not form a cancerous foci, some free disruptive molecules are produced in the body fluid, and this technique can detect them.
In September, researchers at King's College London in London also developed a cMyC technique for detecting heart disease using liquid biopsy, which can be obtained in 15 to 20 minutes.
The study said that two-thirds of patients with chest pain in hospitals are not heart patients. This technique hurts the blood troponin value of the testee to determine whether the chest pain of the testee is the heart. If you are a mild illness, you can be discharged immediately. This will help reduce the burden on hospitals and patients.
Source: Curiosity Daily
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