Pymetrozine is a pyridine heterocyclic insecticide, which is highly efficient, low-toxic, environmentally friendly, and accords with the current development direction of pesticides. The insecticide has a unique mode of action, has no knockdown activity, and does not produce direct toxicity to the insects, but once insects come into contact with the agent, they immediately stop feeding. Researchers at Dalian University of Technology used ethyl acetate as the starting material, followed by six steps of the hydrolysis and esterification of esters, alkylation of amines, condensation of ketones and hydrazines, hydrolysis of amides, and condensation of amines and aldehydes. A novel and efficient pesticide pymetrozine was synthesized with a total yield of 52.9%. The liquid phase analysis showed that the product purity was 99.95%. According to researchers, even if resistance to organophosphorus and carbamate insecticides has developed, pymetrozine has unique control effects against sucking mouthpart insects, especially aphids, whiteflies, and black-tailed leafhoppers. Can be used for the control of various resistant strains of pests. Due to its high selectivity, low toxicity to mammals, and safety to birds, fish, and non-target arthropods, it shows good prospects for development in comprehensive prevention and control.
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