With the increasing and intensive use of peptides in the biomedical field, there is an increasing demand for labeled and modified peptide species, and quality requirements are increasing. Stable isotope labeling is one of the typical ones. Stable isotope labeling can be used to study peptide metabolic pathways, and can track the changes in the position and quantity of isotopically labeled peptides in vivo or in vitro. Isotope labeling has the advantages of high sensitivity, simple positioning, and accurate quantitation, which makes isotopic modification more and more widely concerned in the fields of medicine and biochemistry.
At present, the isotope-labeled peptides synthesized by our company are mainly C13, N15 two isotopically labeled polypeptides. By directly introducing isotopically labeled amino acids into the peptide chain, the purpose of effectively labeling the entire peptide chain is achieved. The commonly used isotopically labeled amino acids are Tyr. Thr, Lys, Arg, Glu, etc.
An isotopically-labeled polypeptide differs from a normal peptide in that C in one or several amino acids in its structure is substituted by C13 or N is substituted by N15.
The professional team, first-class synthetic purification technology, rigorous work attitude and strict quality requirements are important guarantees for our customers to meet the different purity requirements of isotopically labeled peptides. At the same time, the raw materials (isotopically labeled amino acids) of isotopically labeled peptides are expensive, which makes our synthesis cost high, which directly leads to the high price of this peptide. With the customer first, we strive to meet the needs of customers. National peptide organisms provide micrograms, milligrams to kilograms of quality service.
success case:
Sequence WVQTLSEQVQEELLSSQVTQEL[13C-15N-R]
HPLC analysis:
MS analysis: 
At present, the isotope-labeled peptides synthesized by our company are mainly C13, N15 two isotopically labeled polypeptides. By directly introducing isotopically labeled amino acids into the peptide chain, the purpose of effectively labeling the entire peptide chain is achieved. The commonly used isotopically labeled amino acids are Tyr. Thr, Lys, Arg, Glu, etc.
An isotopically-labeled polypeptide differs from a normal peptide in that C in one or several amino acids in its structure is substituted by C13 or N is substituted by N15.
success case:
Sequence WVQTLSEQVQEELLSSQVTQEL[13C-15N-R]
HPLC analysis:
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Shaanxi Kang New Pharmaceutical co., Ltd. , https://www.bio-pharmacies.com