The efficacy and pharmacological effects of Cistanche

The effect of Cistanche

Cistanche not only has the function of tonifying kidney yang, benefiting blood and invigorating the bowel, but also effectively relieves the symptoms of impotence, weak waist, weak bones, constipation and infertility.

The role of Cistanche

1. Citrus grandis is rich in alkaloids, crystalline neutral substances, amino acids, trace elements, vitamins and other ingredients. It can nourish the kidney yang and benefit essence blood, can suppress the appearance of "yang deficiency" and prevent weight loss. Can effectively prevent and treat men's kidney deficiency impotence, spermatorrhea and premature ejaculation and irregular menstruation, amenorrhea, infertility and other diseases.

2. Cistantine can significantly increase the speed of small intestine advancing, shorten laxative time, and at the same time significantly inhibit the absorption of water in the large intestine, thereby promoting the excretion and excretion of feces, and has a true laxative effect.

3. Citrus also enhances immune function. Cistanche polysaccharide has a significant effect on the formation and activity of human lymphocytes, it can increase the proliferation of lymphocytes, thereby enhancing the body's immune function.

4. Cistanche can also regulate the circulatory system, has the following effects: protection of ischemic myocardium; hypolipidemic, anti-atherosclerotic, antithrombotic; reduce peripheral vascular resistance, expand peripheral blood vessels, lower blood pressure; protect the liver, anti-fatty liver .

5. Phenyl bromide contained in Cistanche is an ingredient that other drugs do not have. It is the most effective ingredient for delaying aging. Cistanche on the body's lower pituitary gland, gonads and other parts of the aging have a significant delay.

Cistanche pharmacology

1. Anti-aging effect

research shows

Cistanche has a certain degree of anti-aging effect. Cistanche can significantly increase the activity of superoxide dismutase (SOD) in mouse erythrocytes, significantly reduce the content of myocardial lipofuscin in mice, and prolong the average life span of fruit flies. Days and maximum life. Decoction of Cistanche decoction 8g/kg gavage mice can significantly increase the activity of Na+, K+-ATPase in erythrocyte membrane, which may be one of the mechanisms of its complement effect.

2. Adjust endocrine, promote metabolism and strong effect

Cistanche can regulate the decrease and increase of hepatic and spleen nucleic acid content in Yang deficiency and yin deficiency animals; it has the function of activating adrenal gland and releasing corticosteroids. Its mechanism may be to enhance the function of hypothalamic-pituitary-ovarian luteal body. Not because they directly stimulate the secretion of pituitary luteinizing hormone, but to increase the pituitary response to LRH and ovarian response to LH. It is suggested that the main significance of traditional Chinese medicine for tonifying the kidney is to improve the regulatory mechanism in the body, and to play an active therapeutic role through the restoration of the internal function of the body itself. Through studies on the effect of Cistanche on the DNA synthesis rate of “Yang-deficiency” animals, it was found that hydroxyurea caused a reduction in the rate of DNA synthesis due to its inhibition of the reduction of nucleotides at the level of diphosphorylation, and protein and energy metabolism caused “yang deficiency”. "Citrus brevifolia may contain a bioactive factor that activates ribonucleotide reductase, which can significantly increase the DNA synthesis rate of "Yang-deficiency" animals and promote the synthesis of RNA; increase the nucleic acid metabolism of the protein; and add it with its dilute ethanol extract. Feeding rats in drinking water can promote growth and development.

3. Effect on the immune system

Cistanche water extract 50mg/kg, 100mg/kg gavage to mice, can significantly increase the weight of the spleen and thymus, and can significantly enhance the phagocytic capacity of peritoneal macrophages, increase the hemolysin and PFC values, increase lymphocyte transformation rate And delayed hypersensitivity index can also increase cAMP levels, reduce cGMP levels, and increase cAMP/cGMP ratio, which may be one of the reasons for its enhanced phagocytosis of peritoneal macrophages.

Cistanche ethanol extract 1.25g/kg, 2.5g/kg (equivalent to crude drug 5.61g/kg, 11.21g/kg) gavage mice for 8 days, the fifth day of sensitization with sheep red blood cells, can significantly inhibit the spleen The number of plaques in the cells. Cistanche extract and total flavonoids of Epimedium have an additive effect on the promotion of lymphation in immunosuppressed mice, and can enhance the immune ability of model mice.

4. Other effects

Cistanche water leaching solution, ethanol-water leaching solution and alcohol leaching solution have an anti-hypertensive effect on anesthetized dogs, cats, rabbits, etc. Cistanche deserticola promotes saliva secretion and respiratory palsy in mice, and promotes saliva secretion as an organic acid-like substance. The component of respiratory paralysis may be fleas.

Cistanche related selection

1. Ji Chuan Jian ("King Yue Quan Shu Xin Fang Bazhen"), attending weak kidney, weak stool, urine clear, backache cold.

2. Dihuang Yinzi ("the Emperor Su asked Xuanming Theory"), nourishing kidney yin, kidney yang, open phlegm, attending phlegm card, tongue can not be spoken, enough to use, dry mouth do not want to drink.

3 extremely yam pills ("Prepare for the Golden Prescription"), spleen and stomach, Peiyuan Zishen, Indulgence attending injury, body weight loss, backache knee soft, head dark tinnitus, diet tasteless.

4. Modified four-pound pill ("three due to a disease syndrome theory"), attending liver and kidney deficiency, hot prostitution in the inside, bones and tendons soft, walking weakness, Yaoxisuanruan, hot flashes for hours, eating tasteless.

5. Ruan Sizi Pills ("Taiping Huimin Hefei Banfang"), attending kidney qi deficiency, five labor and seven injuries, lower abdominal cramps, limbs shortness of breath, night dream panic, mental drowsiness, moodiness, long urine, atrioventricular absent Lift etc.

6. Cuo Sizi San ("Medical Medicine must read"), attending bladder deficiency, urine can not help or too much.

7. Cistanche Pills ("Medical Heart"), attending men's five-workers and seven injuries, impotence can not afford, urine dripping, red urine color.

8. Ginseng Pills (“National Formulation of Traditional Chinese Medicines and Chinese Medicines”), Indications are physical and mental fatigue, tinnitus and heart palpitations, nocturnal emission, premature ejaculation, anemic chlorosis, and neurasthenia.

9. Runchang Pills (“World Medicine Efficacy”), attending less fluid loss, constipation.

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