Aflatoxin detection solutions in milk and dairy products

Aflatoxins are a class of chemically similar compounds, all of which are derivatives of dihydrofuran coumarin. They are found in soil, animals and plants, and various nuts. They are particularly susceptible to contamination of peanuts, corn, rice, and soybeans. Grain and oil products such as wheat are a class of mycotoxins that are the most toxic in mycotoxins and are extremely harmful to human health. The aflatoxin mainly contains B ₁ , B ₂ , G ₁ , G ₂ , M ₁ , M ₂ and the like. Aflatoxin M ₁ is a metabolite derived from the hydroxylation of aflatoxin B ₁ in the body, wherein M ₁ and M ₂ are mainly present in milk. The new national standard GBT5009.24-2016 "Determination of aflatoxin M in the food safety national standard food" clearly specifies the detection of aflatoxin M.

High performance liquid chromatography

PriboFast ^® Immunoaffinity Column

• Use high specificity and high affinity monoclonals;

• 3ml column tube with high column capacity, which effectively improves purification efficiency;

• Meet the domestic and international mycotoxin limit standards;

• Recovery rate : > 90%;

• Repeatability (CV%): <5%;

• Stability: 18 months;

Take the milk powder sample as an example:

Instruments and consumables for high performance liquid chromatography :

Enzyme-linked immunosorbent assay

PriboFast ^® enzyme-linked immunosorbent assay kit

• Direct competition ELISA is used, the detection time is short, and the whole reaction process is about 20 minutes;

• Accuracy is close to HPLC method, wide range of quantitation, 0.125ppb~24ppb;

• Repeatability is good, the error between batches is 3%, and the error between batches is 9%;

• High sensitivity: 0.03ppb, recovery: 89%~92%;

• Meet the latest standards for mycotoxin testing;

• High stability for up to 12 months.

Pribolab ^® aflatoxin M ₁ test kit for procedures

Instruments and consumables required for enzyme-linked immunosorbent assay :

Bone Screw

Bone screws, also known as fracture fixation screws, are commonly used in clinical practice to fix orthopedic implants.

Bone screws are usually used to fix internal fractures or dislocations by directly screing into two different bone blocks or fixing an internal implant such as a bone plate to achieve fracture fixation, position the bone and promote its healing. Bone screws are used in a wide range of areas, including the shoulder, elbow, hip, knee, spine, etc. For example, pedicle screw systems are used for spinal fusion, and compression bone screws are commonly used for foot and ankle surgery or fixation of other fractures under pressure. Similar to traditional mechanical screws, the main structures of bone screws also include nail cap, nail body, and nail tip. Screws can be used to fix bone plates or bone fragments. When used for the former, they are called plate screws, and when used for the latter (to prevent the collapse of bone fragments), they are called positional screws. The latter can be inserted into the plate holes, and can be placed on the bone alone (also known as compression screws). Compression screws can be used to increase interfragment pressure.

(1) The screw cap

The screw cap has three main functions: the first is to optimize the force. The protruding cap makes the contact area between the screw and bone larger, increases the load area, optimizes the local force at the screw insertion site, and reduces the risk of bone rupture caused by excessive stress. The second is the positioning effect. The prominent cap makes the bone nail can only be screwed into a certain depth to prevent the whole bone nail from being screwed into the bone completely. The third function is to provide the position of force application by rotating the force groove at the cap to move the bone nail forward and drive it into the bone. Now, the force groove is mostly inner hexagonal, which does not require axial force to maintain the actuator in the center position and is suitable for a wider range of fractures.

(2) Screw the body

The size of the nail body determines the strength and fatigue resistance of the bone nail. The larger the diameter of the nail body, the stronger the strength will be, and the corresponding fatigue resistance will be better. In addition to the diameter of the nail body, the pitch and tooth depth of the screw body thread are also the key parameters of the nail body design. Different thread design has an important effect on the pressure and occlusal performance of the screw.

(3) Screw tip

Tapping is the process of phalangeal nail cutting thread in the bone. According to the shape of the nail tip, the bone nail can be divided into self-tapping nail and non-self-tapping nail. The nail tip of the self-tapping nail is sharper and can be directly screwed into the bone without pre-drilling. Usually, self-tapping screws are used for Cancellous bone, and the bone is compressed when the screw is inserted, so as to increase the bone density of the occlusal part locally and enhance the occlusal effect. However, when inserting screws in Cortical bone, the screw channel is generally pre-punched, and then the bone screw is screwed. Usually, the self-tapping screw is not directly used to prevent the bone screw from being stuck or damaged because the cortical bone is too hard.

Bone Screw,Cancellous Screw,screws in bone,Cortical Screw

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